Agilent
1100 Series HPLC
Provisional entry — research in progress
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The Agilent 1100 Series HPLC system is a modular high-performance liquid chromatography platform introduced in 1995. The Agilent 1100 Series sets the industry standard for HPLC analysis. The Agilent 1100 Series combines long expertise in chemical analysis with leading computer technology to expand networking technology into the laboratory.[1][2]
Produced
1995–
Power
100 – 120 or 220 – 240 VAC, ± 10 %[4]
Vacuum
0.2 ml/min to 10 ml/min[1]
Performance
Typically < 0.5 % RSD from 5 – 100 µl[2]
Optics
190 – 950 nm[2]
What it is
How it works
The Agilent 1100 Series uses modular pumps for solvent delivery, autosamplers for injection, a column compartment for temperature control, and detectors for signal measurement.[1][4][6]
The Agilent 1100 Series supports handheld controller operation, ChemStation control, and networked control through a local area network.[1][4]
Where it fits in the process flow
Applications
The Agilent 1100 Series is used for routine HPLC analysis and can be configured for standard analytical work, capillary LC, preparative work, and LC/MS-related operation.[1]
The Agilent 1100 Series supports detectors for variable wavelength, diode-array, fluorescence, refractive index, and mass-selective measurements.[1][4][6]
What do the numbers mean?
Power & electrical1
Vacuum & pumping14
- Modules/Components
- Isocratic pump (G1310A), binary pump (G1312A), quaternary pump (G1311A), capillary pump, preparative pump, standard autosampler (G1313A), well-plate autosampler, thermostatted micro autosampler, micro well-plate autosampler, thermostatted column compartment (G1316A), vacuum degasser (G1322A), variable wavelength detector (G1314A/B), diode array detector (G1315A/B), multiwavelength detector, fluorescence detector (G1321A), refractive index detector (G1362A), mass selective detector LC/MSD VL/SL, LC/MSD Trap, controllers, handheld control module, ChemStation software[1]
- Dimensions (Isocratic Pump, VWD, FLD)
- 345 mm × 435 mm × 140 mm (13.5 × 17 × 5.5 inches) (W × D × H)[4]
Optics & imaging7
- Detectors
- Variable Wavelength (VWD), Multiwavelength (MWD), Diode Array (DAD), Fluorescence (FLD), Refractive Index (RID), Mass Selective (LC/MSD VL/SL, LC/MSD Trap)[1]
Performance2
Control & software2
- Control and Data Handling
- Handheld controller, Agilent ChemStation (2D/3D), Cerity Networked Data System, ChemStation Plus, Security Pack for 21 CFR Part 11 compliance[1]
- Communications
- Controller-area network (CAN), GPIB, RS-232C, APG Remote (ready, start, stop, shut-down), LAN (optional)[2]
Dimensions & facilities1
- Module dimensions (width × depth × height, most modules)
- 345 × 435 × 140 mm (13.5 × 17 × 5.5 in)[4]
Configuration & options7
- Autosampler Injection Volume (Standard)
- 0.1 – 100 μl standard range, up to 1800 μl or 5000 μl with extension[1]
Vintage & configurations
- 1995Production start[2]
Introduced in 1995.
Documented models & variants
| Designation | Generation | Vintage | Changes | Source |
|---|---|---|---|---|
| Isocratic Pump G1310A | — | — | Workhorse for routine QA/QC; upgradable to quaternary pump. | cdn.labwrench.com[1] |
| Binary Pump G1312A | — | — | High-pressure mixing; rapid reproducible gradients; flow range 0.1–5 ml/min. | spectralabsci.com[2] |
| Quaternary Pump G1311A | — | — | Highest flexibility in solvent mixing; flow range 0.2–10 ml/min. | cdn.labwrench.com[1] |
| Capillary Pump | — | — | Optimized flow rates from 1 µl/min to 100 µl/min (capillary mode); normal mode up to 2.5 ml/min. | cdn.labwrench.com[1] |
| Preparative Pump | — | — | Isocratic high performance pump with two parallel pistons; flow rates up to 100 ml/min at 400 bar. | cdn.labwrench.com[1] |
| Standard Autosampler G1329A | — | — | Sample capacity up to 100 vials; injection volume 0.1–100 µl; thermostatted version available. | spectralabsci.com[2] |
| Well-Plate Autosampler (WPALS) G1367A | — | — | Optimized for high sample throughput with fast injection cycles and overlapped injections. | cdn.labwrench.com[1] |
| Diode Array Detector G1315B | — | — | 1024-element photodiode array; wavelength range 190–950 nm; deuterium and tungsten lamps. | spectralabsci.com[2] |
| Variable Wavelength Detector G1314A | — | — | Standard flow cell with 10 mm path length, 14 µl volume, 40 bar max pressure. | gmi-inc.com[4] |
| Fluorescence Detector G1321A | — | — | Simultaneous quantitative and qualitative information from up to four signals; real-time spectra. | cdn.labwrench.com[1] |
| Refractive Index Detector G1362A | — | — | For GPC and other RI-sensitive applications. | cdn.labwrench.com[1] |
| Binary VWD System | — | — | Configuration with binary pump and variable wavelength detector. | gmi-inc.com[5] |
| Binary DAD System | — | — | Configuration with binary pump and diode array detector. | gmi-inc.com[5] |
| Quaternary VWD System | — | — | Configuration with quaternary pump and variable wavelength detector. | gmi-inc.com[5] |
| Quaternary DAD System | — | — | Configuration with quaternary pump and diode array detector. | gmi-inc.com[5] |
What does it need to run?
Site utility requirements, footprint, and infrastructure needed to install and operate this tool. Sourced from public records.
- Flow range (isocratic pump)0.2 ml/min to 10 ml/min[1]
- Flow range (binary pump)0.1 – 5.0 ml/min (settable 0.001 – 5 ml/min)[2]
- Pressure range (binary pump)0 – 400 bar (0 – 5880 psi)[2]
- Flow precision (binary pump)< 0.3 % RSD (typically 0.15 %) at 1 ml/min[2]
- Module weight (isocratic pump, VWD, TCC)11.0 kg (25.0 lbs) each[4]
- Line voltage100 – 120 or 220 – 240 VAC, ± 10 %[4]
- Modules/ComponentsIsocratic pump (G1310A), binary pump (G1312A), quaternary pump (G1311A), capillary pump, preparative pump, standard autosampler (G1313A), well-plate autosampler, thermostatted micro autosampler, micro well-plate autosampler, thermostatted column compartment (G1316A), vacuum degasser (G1322A), variable wavelength detector (G1314A/B), diode array detector (G1315A/B), multiwavelength detector, fluorescence detector (G1321A), refractive index detector (G1362A), mass selective detector LC/MSD VL/SL, LC/MSD Trap, controllers, handheld control module, ChemStation software[1]
- Pump Flow Range (Isocratic)0.001 – 10 ml/min[1]
- Pump Flow Range (Binary)0.001 – 5.0 ml/min[1]
- Pump Flow Range (Quaternary)0.001 – 10 ml/min[1]
- Pump Flow Range (Capillary)0.01 μl/min – 2.5 ml/min[1]
- Pump Flow Range (Preparative)0.001 – 100 ml/min[1]
- Pressure Range (Binary/Isocratic/Quaternary)0 – 400 bar (0 – 5880 psi)[2]
- Dimensions (Isocratic Pump, VWD, FLD)345 mm × 435 mm × 140 mm (13.5 × 17 × 5.5 inches) (W × D × H)[4]
- Weight (Isocratic Pump)11.0 kg (25.0 lbs)[4]
Where are the manuals?
Generated from public-source data on file. Enter your email to access — nothing is published; details are routed privately.
Not publicly documented
Field notes
No research found yet — worked with this tool? Share what you know.
Frequently asked questions
When was the Agilent 1100 Series introduced?
The Agilent 1100 Series was introduced in 1996.[1]
What pump types are available for the Agilent 1100 Series?
Available pump types include isocratic, binary gradient, quaternary, capillary, and preparative pumps.[1]
What is the flow range of the quaternary pump?
The quaternary pump provides a flow range from 0.2 ml/min up to 10 ml/min.[1]
What detectors are available for the Agilent 1100 Series?
Detector options include variable wavelength, diode-array, fluorescence, refractive index, and mass selective (single quadrupole and ion trap) detectors.[1]
What is the standard configuration of the G1380AA Value System?
The G1380AA Value System standard configuration includes a G1310A isocratic pump, G1328A manual injector, G1314A variable wavelength detector, and G2220AA 2D-Value Solution ChemStation.[4]
Not publicly documented
The following facts about the 1100 Series HPLC are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.
The control-system platform and OS era of the 1100 Series HPLC are not on record.
Answerable by: an engineer who operated it or OEM installation records
No publicly documented failure modes or field errata for the 1100 Series HPLC are on record.
Answerable by: a field service engineer, process engineer, or maintenance technician
The process node or technology generation of the 1100 Series HPLC is not on record.
Answerable by: an OEM datasheet or a fab qualification report
No publicly documented compatible parts, consumables, or accessories for the 1100 Series HPLC are on record.
Answerable by: an OEM parts catalog or a service engineer
No publicly hosted manuals, SOPs, or datasheets for the 1100 Series HPLC are on record.
Answerable by: university cleanroom staff or an OEM application specialist
No research found yet — worked with this tool? Share what you know.
Sources & citations
Sources (6)Every fact above is drawn from these public sources
- [1]cdn.labwrench.com — cdn.labwrench.comcdn.labwrench.com
- [2]spectralabsci.com — spectralabsci.comspectralabsci.com
- [3]Inventory photo
- [4]gmi-inc.com — gmi-inc.comgmi-inc.com
- [5]gmi-inc.com — gmi-inc.comgmi-inc.com
- [6]Refurbished Agilent 1100 Series HPLC System complete - IET - Refurbished Analytical Laboratory Equipment - Used Lab Equipment — ietltd.comietltd.com
Last updated Sep 24, 2026.